Toronto, Canada June 19: Canadian researchers in a clinical trial have developed a vaccine for disease caused by Ebola virus.
The study found that the recombinant vesicular stomatitis virus-Zaire Ebola virus (rVSV-ZEBOV) is well-tolerated and showed no safety concerns.
The rVSV-ZEBOV is a recombinant, replication-competent vesicular stomatitis virus-based candidate vaccine expressing a surface glycoprotein of Zaire Ebola virus.
Only mild to moderate side-effects were seen, with only three severe reactions, including a headache, diarrhea, and fatigue, which were completely resolved, the researchers said.
Further, participants reported high antibody levels in six months after the immunization.
"The results of this trial were positive and very promising. All three dose levels of the rVSV Ebola vaccine were well-tolerated by participants, and no safety concerns were identified," said lead author May ElSherif, Canadian Centre for Vaccinology an integrated collaborative vaccine research center in Nova Scotia.
Data from this trial and others indicated an optimum dose of 20 million plaque-forming unit (PFU) that will be assessed among people with compromised immune systems in areas where Ebola is endemic.
The 2013-2016 Ebola virus outbreak in West Africa was the most widespread in history.
There were some latest clusters of Ebola cases in Africa and more expected as survivors may still spread the virus to uninfected people, the researchers said.
For the trial, published in CMAJ (Canadian Medical Association Journal), the team involved 40 healthy people aged 18 to 65 years and looked at the safety of the vaccine and the lowest dose required for an immune response after injection with one of three doses.
Given the ongoing presence of Ebola, "these facts underscore the importance of continuing efforts and collaborations that may ultimately lead to licensed Ebola vaccines that would protect humans and prevent or control outbreaks in the future," ElSherif added.
Hyderabad, May 20: Tollywood bubbly Actress Raashi Khanna has launched the first song of the film Jambalakidi Pamba, which features Srinivas Reddy and. The actress said the song is really nice to ..Written by : IANS | 05:55 PM
Hyderabad, May 19: Hyderabad Metro Rail (HMR) will become the first metro in the country to provide Electric Vehicle (EV) Charging Stations. HMR keen to a step forward to create amazing achievemen ..Written by : IANS | 04:31 PM
Hyderabad, May 20: Tollywood Macho Star Manchu Manoj has celebrated his birthday on today, in this many of the celebrities has been wished the Young actor on thier Micro Biological sites. His fathe ..Written by : IANS | 03:53 PM
Hyderabad, April 12: Nagarjuna's song "Ninnu Roddu Meeda Chusnadi Laggayithu" one of the most popular songs in 1990's. The Song has got a tremendous response in that time. The SOng was super hit film ..Written by : IANS | 05:04 PM
Hyderabad, Apr 10: Preparations related to NTR Rama Rao biopic are ongoing. Bala Krishna is playing the role of NT Rama Rao while the rest of the cast has to be finalized. The selection process for th ..Written by : IANS | 02:13 PM
Hyderabad, Apr 03: Power star Pawan Kalyan has congratulated on the hit of Rangasthalam team here on today. Pawan spoke to Charan after watching "Rangasthalam" on the special screen, he told that h ..Written by : IANS | 04:47 PM
Hyderabad, Mar 26: The Tollywood Gorgeous actress Anushka Shetty had a fabulous start to 2018 with the solid success of Bhaagamathie. Although there have been several rumors on her future projects ..Written by : IANS | 03:04 PM
Chennai, May 20: Actor-turned-politician Raji ..
New Delhi, May 20: The public sector BSNL wil ..
Bangalore, May 20: Ending the long-lived high ..
New Delhi, May 19: Congress President Rahul G ..
Bengaluru, May 18: In a shocking comment, Mah ..
Bangalore, May 19: Just two days after taking ..
Bengaluru, May 19: BS Yeddyurappa's tenure as ..
Bengaluru, May 19: The floor test in the Karn ..
Bangalore, May 19: I cannot forget the love a ..
Bengaluru, May 19: Congress MLAs Anand Singh ..
Washington, May 18: US President Donald Trump ..
Washington, May 18: Trump who is know for his ..
New Delhi, May 17: In a major development tow ..
New Delhi, May 16: Facebook took moderation a ..
London, May 15: Chinese mobile maker Honor on ..
San Francisco, May 13: After reports surfaced ..
Beijing, May 13: As it prepares to file an in ..
Dhaka, May 12: Bangladesh launched its first ..
Kathmandu, May 12: Indian Prime Minister Nare ..
San Francisco, May 12: The giant Social media ..
New Delhi, May 20: Mahendra Singh Dhoni enjoy ..
Hyderabad, May 18: The Telangana government h ..
New Delhi, May 18: The International Cricket ..
Barcelona, May 16: FC Barcelona's star player ..
New Delhi, May 16: Continuing its Dominant sh ..
New Delhi, May 15: Plea by former cricketer S ..
Chennai, May 15: Mahendra Singh Dhoni is soon ..
Reykyavik, May 13: FIFA World Cup debutant Ic ..
New Delhi, May 09: As we knew that, The BCCI ..
New Delhi, May 09: The BCCI selectors met in ..
Hyderabad, May 20: Nowadays, Wearing a trendy ..
Hyderabad, May 19: Bharti Airtel is now offer ..
Some healthy facts of daily walk~ 1- Daily ..
New Delhi, May 16: Today, many people are una ..
New Delhi, May 15: Realme is a new brand ente ..
Mumbai, May 14: India Biggest Telecom Operato ..
Hyderabad, May 07: If you own a smartphone, t ..
Hyderabad, May 6: Weight loss is one of the l ..
Hyderabad, May 06: Losing Belly fat is not as ..
Hyderabad, April 30: Good news for the Indian ..