Insulin for one month

     Written by : SMTV24x7 | Wed, Jun 07, 2017, 12:57 PM

Insulin for one month

A good news for the Diabetes people, as they are getting the insulin for one month period, According to the Scientists.

Coming to details, Scientists, including one of the Indian-origin, have developed a technology that may provide weeks of glucose control for diabetes with a single injection, which would be a dramatic improvement over current therapies.

In primates, the treatment has been shown to last for weeks, rather than days, researchers at Duke University in the US said.

By creating a controlled-release mechanism for a drug and optimizing its circulation time in the body, the new biopolymer injection has the potential to replace daily or weekly insulin shots with once-a-month or twice-a-month treatments for type 2 diabetes, they said.

Many current treatments for type 2 diabetes use a signaling molecule called Glucagon-like peptide-1 (GLP1) to cause the pancreas to release insulin to control blood sugar. However, this peptide has a short half-life and is cleared from the body quickly.

Researchers, including Ashutosh Chilkoti, from Duke University, have created a technology that fuses GLP1 to a heat-sensitive elastin-like polypeptide (ELP) in a solution that can be injected into the skin through a standard needle.

Once injected, the solution reacts with body heat to form a biodegradable gel-like "depot" that slowly releases the drug as it dissolves.